The Girls Next Door Hugh Hefner died from cardiac arrest and was dealing with E. coli infection 10/04/2017 Hugh Hefner died after going into cardiac arrest and experiencing respiratory failure, a death certificate for the magazine mogul has unveiled. Read More RELATED NEWS Hugh Hefner died from cardiac arrest and was dealing with E. coli infectionKendra Wilkinson, Bridget Marquardt, Pamela Anderson, Kim Kardashian and more mourn Hugh HefnerHugh Hefner, 'Playboy' founder and former 'The Girls Next Door' star, dies at age 91 TAGS: Crystal Harris Hugh Hefner Kendra Wilkinson Pamela Anderson Jared Leto Brett Ratner